![]() Damage to the main blood vessel leading from the heart (aorta).Tumor of the myelin sheath (schwannoma).Causes related to nerve damage in this region may include: This neuron path extends from the spinal column, across the upper part of the chest and into the side of the neck. Cyst in the spinal column (syringomyelia).Diseases that cause the loss of the protective sheath on neurons (myelin).Problems in this region that can disrupt nerve function related to Horner syndrome include: This neuron pathway leads from the hypothalamus at the base of the brain, passes through the brainstem and extends into the upper portion of the spinal cord. The nerve pathway affected by Horner syndrome is divided into three groups of nerve cells (neurons). The sympathetic nervous system regulates heart rate, pupil size, perspiration, blood pressure and other functions that enable you to respond quickly to changes in your environment. Horner syndrome is caused by damage to a certain pathway in the sympathetic nervous system. Muscle weakness or lack of muscle control.Get emergency care if signs or symptoms associated with Horner syndrome appear suddenly, appear after a traumatic injury, or are accompanied by other signs or symptoms, such as: It is important to get a prompt and accurate diagnosis. Change in color on the affected side of the face that would typically appear from heat, physical exertion or emotional reactionsĪ number of factors, some more serious than others, can cause Horner syndrome.Lighter iris color in the affected eye of a child under the age of 1.ChildrenĪdditional signs and symptoms in children with Horner syndrome may include: Signs and symptoms, particularly ptosis and anhidrosis, may be subtle and difficult to detect. Little or no sweating (anhidrosis) on the affected side of the face.Slight elevation of the lower lid, sometimes called upside-down ptosis.Little or delayed opening (dilation) of the affected pupil in dim light.A notable difference in pupil size between the two eyes (anisocoria).But further testing may be needed if there are definite signs of concern.Horner syndrome usually affects only one side of the face. Most of the time young children with anisocoria do not have other abnormalities and we'll watch them carefully over time. ![]() For this reason, unequal pupil sizes should prompt a complete eye exam. The most pressing concern with Horner’s Syndrome in young children is a type of cancer called Neuroblastoma that can happen along the spinal cord in the neck and affect that sympathetic nerve. Horner’s syndrome may be most commonly caused by this nerve not forming correctly during development or from birth trauma to the neck. This can result in several abnormalities including anisocoria, ptosis (droopy eyelid), and asymmetric facial flushing. In young children, our biggest concern is looking for signs of something called Horner’s syndrome, where a nerve, called the sympathetic nerve, coming up to the face from the neck is not functioning properly. Unequal pupils can also sometimes occur as a result of exposure to some medications or drugs that affect pupils size. In some people, this could be normal for them and not of any concern, though in these cases the difference in size is usually relatively small. "Anisocoria" is the medical term for unequal pupil sizes.Īnisocoria may be present for a number of reasons. ![]() Either the parents or the primary care doctor may notice this difference early in life. We often see new young patients to evaluate one pupil being larger than the other.
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